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PUMA BH3

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Name PUMA BH3
Cat.NO. ONP10048
Size 1
Purity ≥ 95%
Price $126
Storage -20°C
Molecular Weight 3049.3
Sequence (One-Letter Code) EEQWAREIGAQLRRMADDLNAQYER
Sequence (Three-Letter Code) Glu-Glu-Gln-Trp-Ala-Arg-Glu-Ile-Gly-Ala-Gln-Leu-Arg-Arg-Met-Ala-Asp-Asp-Leu-Asn-Ala-Gln-Tyr-Glu-Arg
Description This is a PUMA BH3 domain peptide. PUMA proteins bind Bcl-2, localize to the mitochondria, and induce cytochrome C release and apoptosis in response to p53. PUMA may be a direct mediator of p53-induced apoptosis.